When Lisa Mastramico needed relief for her ailing tabby, Little Kitty, she turned to an unlikely source: marijuana.

At 12 years old, the cat had arthritis. For a long while she spent her days hiding in a closet, where Ms. Mastramico had built her a bed of plush blankets. After trying various supplements that proved ineffectual, she went to a meeting for Women Grow, an industry group for cannabis entrepreneurs.

She was not sold on the idea right away. “My concern was that it’s not my place to get my cat high,” said Ms. Mastramico, the director of a public access television network in Long Beach, Calif.

But with Little Kitty becoming increasingly isolated, it was time to give it a try. She got a medical marijuana card and purchased two edible oils made for pets and derived from cannabis that she squirts into her pet’s mouth.

Little Kitty doesn’t hide anymore. In fact, she’s more like her old self: sunbathing on the living room carpet, playing with Ms. Mastramico’s other cat, Valentina. “When I’ve given it to her, she’s never acted high: falling face-first into her food bowl, chowing down,” Ms. Mastramico said. “She comes out and socializes, wants to be in your lap, wants to be petted. It’s a very noticeable difference.”
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